Review on formulation and evaluation of polyherbal toothpaste (KEY IJP************839)

• Akshay Satish Gholap

Abstract

This research endeavors to create a herbal toothpaste incorporating natural elements such as Guava leaves, Neem stem, Kalmi bark, Babul leaves, etc., traditionally employed for dental hygiene. The preference for formulations with natural ingredients stems from the perception of their safety compared to synthetic counterparts. The assessment of the formulated herbal toothpaste encompasses organoleptic and physical characteristics, including color, odor, taste, pH, spreadability, moisture content, fineness, and foam ability.Historically employed for dental hygiene, natural ingredient-infused formulations are perceived as safer compared to synthetic drugs.The antimicrobial assessment against Staphylococcus aureus indicates that the herbal toothpaste formulation demonstrated significant efficacy, with a zone of inhibition (ZOI) measuring 19.7 mm at a minimum inhibitory concentration (MIC) of 25gmL. The findings of this study suggest a comparable and compelling preference for the formulated herbal toothpaste when compared to commercial products such as Colgate, Dabour Red, and Dantkanti.Toothpaste serves a primary role in oral care, aiding in the upkeep of oral hygiene. It acts as an abrasive, eliminating dental plaque and food particles from the teeth, contributing to the prevention of halitosis by masking or removing it. Additionally, toothpaste releases active substances such as fluoride, assisting in the prevention of tooth and gum diseases like Gingivitis. The toothbrush's mechanical action, coupled with the toothpaste's included excipients, predominantly facilitates the cleaning process.The toothpaste underwent assessment for various factors such as uniformity, spreadability, foaming ability, stability, pH, moisture content, volatile matter, and more. The evaluation focused on both organoleptic and physical attributes to ensure it possesses the necessary features for effective use against dental issues.