REVIEW ON POLYHERBAL DUSTING POWDER (KEY IJP************675)

• Chaudhari Sumeet Santosh

Abstract

The main goal of the work was to formulate and evaluate an antimicrobial polyherbal dusting powder. A dusting powder was formulated in this study. The powder was prepared by mixing everything ingredients in a mortar. The prepared dust was then evaluated for various parameters such as physical properties (color, smell, grit, appearance), solubility, Ph., micrometric properties such as particle size, surface area, density (bulk, tapped), angle of repose, Carr index, Hausner ratio, volume (bulk, tapped). It has been tested for antimicrobial activity against microorganisms such as Escherichia coli and Staphylococcus aureus. A mixed culture of the above two microorganisms was used for the microbiological test by the good diffusion plate method. These antimicrobial products have been tested based on the pathogenesis caused by various microorganisms. These microbes were cultured in a suitable nutrient medium for their growth. The sample was prepared by dissolving 1 g of powder in 10 ml of water. The sample was then transferred to the solidified agar medium, and pre-sterilized in an autoclave. Then the plates were coated with bacterial culture and kept in an incubator at 37C for 48 hours to grow bacterial cultures. After the incubation period growth of microbes and their zone of inhibition surrounding the preparation was observed and measured. The formulation was found to be specifically effective against microbial strains. Primarily essential oils were highly effective against all microorganisms, namely E. coli and S. aureus. We concluded that the polyherbal backfill formulation was effective in antimicrobial activity and should be explored in the treatment of various topical skin conditions. Polyherbal formulations have gained considerable attention in traditional medicine for their synergistic therapeutic effects. In this study, a polyherbal dusting powder was developed using a combination of potent medicinal herbs known for their dermatological benefits. The powdered formulation was prepared using a standardized process and evaluated for physicochemical properties, microbial contamination, and skin compatibility. The polyherbal dusting powder exhibited desirable characteristics such as good flowability, uniform particle size distribution, and absence of microbial contamination. Furthermore, skin compatibility testing revealed no signs of irritation or adverse reactions, indicating its safety for topical application. The polyherbal dusting powder holds promise as a natural alternative for managing various dermatological conditions, with potential implications for improving skin health and well-being. Further clinical studies are warranted to validate its efficacy and safety for therapeutic use.