PHARMACOLOGICAL ACTIVITY OF MORPHOLINE DERIVATIVES AS AN IMPORTANT SCAFFOLD IN MEDICINAL CHEMISTRY: A REVIEW (KEY IJP************765)

• Kolichala Niranjan

Abstract

Morphine derivatives are biologically active chemical molecules with unique structures that have been found in a variety of medications. Morpholine derivatives are widely used as antibacterial, antiemetic, analgesic, anti-inflammatory, anti-pyretic, antiglaucoma, mTOR, anti-platelet, antitumor, proliferative, ACR-induced neurotoxicity, anticancer, antifungal, FGFR3 Kinase, antituberculosis, antimalarial, antirypanosomal, antioxidant, hypolipidemic, hypocholesterolemic, and anti-HIV activity due to their extraordinary action and terminal pharmacophore of action.