Rabies: Understanding the Virus and Its Impact on Public Health (KEY IJP************569)

• Md Azhar Shadab, Syed Abuzar Rizvi ,Raja Rashid Riaz ,Mohsan Habib,Saniya Siddique ,Laiba Noor,Turusbekova Akshoola Kozmanbetovna,Parpieva Takhmina Makhmatkalylovna

Abstract

The rabies virus (Rabies lyssavirus) is the primary vector of the deadly viral disease rabies, which is endemic in many parts of the world, especially Asia, Africa, and Latin America. Rabies is primarily spread by the bite of an infected animal and causes encephalitis, which can lead to death if treatment is not received. Rabies's incubation period can range from weeks to months, and its early symptoms, which include fever and headache, often mimic those of other viral infections. As the infection worsens, neurological symptoms like agitation, hydrophobia, and paralysis develop, and once clinical symptoms appear, rabies is almost always fatal.Post-exposure prophylaxis (PEP), which consists of a series of rabies vaccinations and, if required, rabies immune globulin (RIG), can prevent rabies. The most successful method for lowering the number of human rabies cases has been the vaccination of household animals, especially dogs. Rabies is still a major worldwide health concern even with the availability of efficient vaccines and treatment methods, especially in areas with little resources. By 2030, the World Health Organization (WHO) wants to eradicate human rabies deaths by expanding access to post-exposure care, education, and vaccine. To improve rabies control and eventually eradicate the illness, more research on vaccines, diagnostic equipment, and antiviral treatments is essential.